Lab Contact Information
Sorenson Molecular Biotechnology Building (SMBB), 4th Floor
36 South Wasatch Drive
Salt Lake City, UT 84112
Goal: To use engineering approaches to understand how information is processed in the brain and to translate this knowledge into biomedical devices to improve the human condition.
The Neuronal Dynamics Laboratory, led by USTAR Professor of Bioengineering John A. White, Ph.D., uses engineering approaches to understand how information is processed in the brain, with the goal of exploiting these findings to improve the human condition. Methods include: computational modeling of neuronal networks; the design and construction of instruments that interact with human subjects and biological preparations in real time at high clock speeds; and electrophysiological and optical techniques for recording detailed information from single neurons and large neuronal networks.
Six interdisciplinary research groups that focus on neural information processing - Dorval, Rabbitt, Taha, Wachowiak, White, and Wilcox Labs - received matching funds from the U of U to purchase an integrated system for optical and electrophysiological studies in vivo. “These diverse, systems neuroscience groups will utilize the shared equipment to develop new techniques, tools, and software for intracellular recordings, optical stimulation, and intracellular recordings,” explains John White, Ph.D., Director, Neuronal Dynamics Laboratory. READ MORE
One in 26 people will have a seizure in their lifetime. Nearly half will go through the unpredictable and sometimes life-threatening experience at least once more, and many will receive a diagnosis of epilepsy. Seizures are caused by groups of neurons in the brain firing uncontrollably. There are many different kinds of seizures that differ based on which neurons are affected, how they are triggered, and how they spread. Nathan Anthony Smith, Ph.D., a postdoctoral scientist for both the Neuronal Dynamics, and Glial-Neuronal Interactions in Epilepsy laboratories at the Brain Institute at the University of Utah, is investigating how astrocytes, long considered inert support cells for neurons, contribute to specific types of seizures. READ MORE